The Centers for Disease Control and Prevention (CDC) has updated its guidance on self-isolation for people who test positive for COVID-19. According to the new guidelines, people who are symptomatic who tested positive for COVID-19 should isolate at home for 10 days after symptoms begin and for 24 hours after their fever has broken. The latest guidance also indicates that a limited number of persons with severe illness and those who are severely immunocompromised may need to isolate for 20 days after symptom onset. Asymptomatic patients should isolate for 10 days from the date of their first positive test. The new guidelines were previewed last week when officials also said the CDC would recommend people do not need to have two negative tests in order to end isolation, which was the previous standard. The CDC continues to recommend a 14-day quarantine period for people who have been in contact with an infected person but don’t have a confirmed infection.